This chapter, titled "The Socio-Technical Challenges of Implementing AI in Hospitals and Clinics," offers a critical and comprehensive review of the barriers preventing the widespread adoption and successful integration of Artificial Intelligence (AI) systems into clinical settings. While AI holds the promise of a technological revolution in healthcare—leading to enhanced patient treatment outcomes, more accurate diagnoses, and significant operational efficiency—its practical implementation is frequently halted by complex, multifaceted obstacles. The article systematically examines the interconnected challenges across five critical dimensions: technical, regulatory, financial, ethical, and organizational.